P Wave Signal‐Averaged Electrocardiography Predicts Recurrence of Paroxysmal Atrial Fibrillation in Patients with Wolff‐Parkinson‐White Syndrome Who Underwent Successful Catheter Ablation: A Prospective Study
Identifieur interne : 000574 ( Main/Corpus ); précédent : 000573; suivant : 000575P Wave Signal‐Averaged Electrocardiography Predicts Recurrence of Paroxysmal Atrial Fibrillation in Patients with Wolff‐Parkinson‐White Syndrome Who Underwent Successful Catheter Ablation: A Prospective Study
Auteurs : Tatsuro Hiraki ; Hisao Ikeda ; Teruhisa Yoshida ; Tomohito Inage ; Masatsugu Ohe ; Hitoshi Ohtsubo ; Manabu Matsumoto ; Takashi Hamada ; Ichiro Kubara ; Tsutomu ImaizumiSource :
- Journal of Cardiovascular Electrophysiology [ 1045-3873 ] ; 2002-10.
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Abstract
P‐SAECG Predicts Recurrence of PAF After Ablation. Introduction: Paroxysmal atrial fibrillation (PAF) frequently occurs in patients with Wolff‐Parkinson‐White (WPW) syndrome. Catheter ablation of the accessory pathway eliminates PAF in some patients, but PAF frequently recurs in other patients. The present study was designed to determine prospectively whether P wave signal‐averaged electrocardiography (P‐SAECG) predicts the recurrence of PAF after successful ablation in patients with WPW syndrome. Methods and Results: Forty‐six patients with WPW syndrome who had episodes of PAF were prospectively followed. SAECG recording was performed on day 7 after successful ablation of the accessory pathway at study entry. Abnormal P‐SAECG for the prediction of recurrence of PAF was defined as a filtered P wave duration > 130 msec. Eleven patients had an abnormal P‐SAECG (group 1), whereas 35 patients (group 2) did not. The two groups did not differ in terms of gender, age, left atrial dimension, and atrial vulnerability as determined by electrophysiologic study. During follow‐up (40 ± 19 months), the recurrence of PAF was noted in 10 (91%) of 11 patients in group 1, whereas it was observed in only 2 (6%) of 35 patients in group 2. Kaplan‐Meier analysis revealed that the recurrence of PAF was significantly more frequent in group 1 than in group 2 (log rank test, P < 0.0001). By multivariate analysis, filtered P wave duration > 130 msec was an independent predictor of recurrence of PAF after ablation (Chi‐square = 21.5, P < 0.0001). Conclusion: The results of this study indicate that P‐SAECG may be useful for identifying patients at risk for recurrence of PAF after successful ablation of WPW syndrome.
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DOI: 10.1046/j.1540-8167.2002.01003.x
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<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">P Wave Signal‐Averaged Electrocardiography Predicts Recurrence of Paroxysmal Atrial Fibrillation in Patients with Wolff‐Parkinson‐White Syndrome Who Underwent Successful Catheter Ablation: A Prospective Study</title><author><name sortKey="Hiraki, Tatsuro" sort="Hiraki, Tatsuro" uniqKey="Hiraki T" first="Tatsuro" last="Hiraki">Tatsuro Hiraki</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Ikeda, Hisao" sort="Ikeda, Hisao" uniqKey="Ikeda H" first="Hisao" last="Ikeda">Hisao Ikeda</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Yoshida, Teruhisa" sort="Yoshida, Teruhisa" uniqKey="Yoshida T" first="Teruhisa" last="Yoshida">Teruhisa Yoshida</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Inage, Tomohito" sort="Inage, Tomohito" uniqKey="Inage T" first="Tomohito" last="Inage">Tomohito Inage</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Ohe, Masatsugu" sort="Ohe, Masatsugu" uniqKey="Ohe M" first="Masatsugu" last="Ohe">Masatsugu Ohe</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Ohtsubo, Hitoshi" sort="Ohtsubo, Hitoshi" uniqKey="Ohtsubo H" first="Hitoshi" last="Ohtsubo">Hitoshi Ohtsubo</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Matsumoto, Manabu" sort="Matsumoto, Manabu" uniqKey="Matsumoto M" first="Manabu" last="Matsumoto">Manabu Matsumoto</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Hamada, Takashi" sort="Hamada, Takashi" uniqKey="Hamada T" first="Takashi" last="Hamada">Takashi Hamada</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Kubara, Ichiro" sort="Kubara, Ichiro" uniqKey="Kubara I" first="Ichiro" last="Kubara">Ichiro Kubara</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Imaizumi, Tsutomu" sort="Imaizumi, Tsutomu" uniqKey="Imaizumi T" first="Tsutomu" last="Imaizumi">Tsutomu Imaizumi</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:5A66D1B186FCDEDD4654A98DA99AD22D0A97BFA0</idno><date when="2002" year="2002">2002</date><idno type="doi">10.1046/j.1540-8167.2002.01003.x</idno><idno type="url">https://api.istex.fr/document/5A66D1B186FCDEDD4654A98DA99AD22D0A97BFA0/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">000574</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">P Wave Signal‐Averaged Electrocardiography Predicts Recurrence of Paroxysmal Atrial Fibrillation in Patients with Wolff‐Parkinson‐White Syndrome Who Underwent Successful Catheter Ablation: A Prospective Study</title><author><name sortKey="Hiraki, Tatsuro" sort="Hiraki, Tatsuro" uniqKey="Hiraki T" first="Tatsuro" last="Hiraki">Tatsuro Hiraki</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Ikeda, Hisao" sort="Ikeda, Hisao" uniqKey="Ikeda H" first="Hisao" last="Ikeda">Hisao Ikeda</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Yoshida, Teruhisa" sort="Yoshida, Teruhisa" uniqKey="Yoshida T" first="Teruhisa" last="Yoshida">Teruhisa Yoshida</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Inage, Tomohito" sort="Inage, Tomohito" uniqKey="Inage T" first="Tomohito" last="Inage">Tomohito Inage</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Ohe, Masatsugu" sort="Ohe, Masatsugu" uniqKey="Ohe M" first="Masatsugu" last="Ohe">Masatsugu Ohe</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Ohtsubo, Hitoshi" sort="Ohtsubo, Hitoshi" uniqKey="Ohtsubo H" first="Hitoshi" last="Ohtsubo">Hitoshi Ohtsubo</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Matsumoto, Manabu" sort="Matsumoto, Manabu" uniqKey="Matsumoto M" first="Manabu" last="Matsumoto">Manabu Matsumoto</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Hamada, Takashi" sort="Hamada, Takashi" uniqKey="Hamada T" first="Takashi" last="Hamada">Takashi Hamada</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Kubara, Ichiro" sort="Kubara, Ichiro" uniqKey="Kubara I" first="Ichiro" last="Kubara">Ichiro Kubara</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author><author><name sortKey="Imaizumi, Tsutomu" sort="Imaizumi, Tsutomu" uniqKey="Imaizumi T" first="Tsutomu" last="Imaizumi">Tsutomu Imaizumi</name><affiliation><mods:affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Cardiovascular Electrophysiology</title><idno type="ISSN">1045-3873</idno><idno type="eISSN">1540-8167</idno><imprint><publisher>Blackwell Science Inc</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2002-10">2002-10</date><biblScope unit="volume">13</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="1003">1003</biblScope><biblScope unit="page" to="1008">1008</biblScope></imprint><idno type="ISSN">1045-3873</idno></series><idno type="istex">5A66D1B186FCDEDD4654A98DA99AD22D0A97BFA0</idno><idno type="DOI">10.1046/j.1540-8167.2002.01003.x</idno><idno type="ArticleID">JCE1003</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1045-3873</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Wolff‐Parkinson‐White syndrome</term><term>atrial fibrillation</term><term>catheter ablation</term><term>prospective study</term><term>recurrence</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">P‐SAECG Predicts Recurrence of PAF After Ablation. Introduction: Paroxysmal atrial fibrillation (PAF) frequently occurs in patients with Wolff‐Parkinson‐White (WPW) syndrome. Catheter ablation of the accessory pathway eliminates PAF in some patients, but PAF frequently recurs in other patients. The present study was designed to determine prospectively whether P wave signal‐averaged electrocardiography (P‐SAECG) predicts the recurrence of PAF after successful ablation in patients with WPW syndrome. Methods and Results: Forty‐six patients with WPW syndrome who had episodes of PAF were prospectively followed. SAECG recording was performed on day 7 after successful ablation of the accessory pathway at study entry. Abnormal P‐SAECG for the prediction of recurrence of PAF was defined as a filtered P wave duration > 130 msec. Eleven patients had an abnormal P‐SAECG (group 1), whereas 35 patients (group 2) did not. The two groups did not differ in terms of gender, age, left atrial dimension, and atrial vulnerability as determined by electrophysiologic study. During follow‐up (40 ± 19 months), the recurrence of PAF was noted in 10 (91%) of 11 patients in group 1, whereas it was observed in only 2 (6%) of 35 patients in group 2. Kaplan‐Meier analysis revealed that the recurrence of PAF was significantly more frequent in group 1 than in group 2 (log rank test, P < 0.0001). By multivariate analysis, filtered P wave duration > 130 msec was an independent predictor of recurrence of PAF after ablation (Chi‐square = 21.5, P < 0.0001). Conclusion: The results of this study indicate that P‐SAECG may be useful for identifying patients at risk for recurrence of PAF after successful ablation of WPW syndrome.</div></front></TEI><istex><corpusName>wiley</corpusName><author><json:item><name>TATSURO HIRAKI M.D., Ph.D.</name><affiliations><json:string>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</json:string></affiliations></json:item><json:item><name>HISAO IKEDA M.D., Ph.D.</name><affiliations><json:string>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</json:string></affiliations></json:item><json:item><name>TERUHISA YOSHIDA M.D., Ph.D.</name><affiliations><json:string>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</json:string></affiliations></json:item><json:item><name>TOMOHITO INAGE M.D.</name><affiliations><json:string>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</json:string></affiliations></json:item><json:item><name>MASATSUGU OHE M.D.</name><affiliations><json:string>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</json:string></affiliations></json:item><json:item><name>HITOSHI OHTSUBO M.D.</name><affiliations><json:string>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</json:string></affiliations></json:item><json:item><name>MANABU MATSUMOTO M.D.</name><affiliations><json:string>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</json:string></affiliations></json:item><json:item><name>TAKASHI HAMADA M.D.</name><affiliations><json:string>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</json:string></affiliations></json:item><json:item><name>ICHIRO KUBARA M.D., Ph.D.</name><affiliations><json:string>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</json:string></affiliations></json:item><json:item><name>TSUTOMU IMAIZUMI M.D., Ph.D.</name><affiliations><json:string>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Wolff‐Parkinson‐White syndrome</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>atrial fibrillation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>catheter ablation</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>recurrence</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>prospective study</value></json:item></subject><articleId><json:string>JCE1003</json:string></articleId><language><json:string>eng</json:string></language><abstract>P‐SAECG Predicts Recurrence of PAF After Ablation. Introduction: Paroxysmal atrial fibrillation (PAF) frequently occurs in patients with Wolff‐Parkinson‐White (WPW) syndrome. Catheter ablation of the accessory pathway eliminates PAF in some patients, but PAF frequently recurs in other patients. The present study was designed to determine prospectively whether P wave signal‐averaged electrocardiography (P‐SAECG) predicts the recurrence of PAF after successful ablation in patients with WPW syndrome. Methods and Results: Forty‐six patients with WPW syndrome who had episodes of PAF were prospectively followed. SAECG recording was performed on day 7 after successful ablation of the accessory pathway at study entry. Abnormal P‐SAECG for the prediction of recurrence of PAF was defined as a filtered P wave duration > 130 msec. Eleven patients had an abnormal P‐SAECG (group 1), whereas 35 patients (group 2) did not. The two groups did not differ in terms of gender, age, left atrial dimension, and atrial vulnerability as determined by electrophysiologic study. During follow‐up (40 ± 19 months), the recurrence of PAF was noted in 10 (91%) of 11 patients in group 1, whereas it was observed in only 2 (6%) of 35 patients in group 2. Kaplan‐Meier analysis revealed that the recurrence of PAF was significantly more frequent in group 1 than in group 2 (log rank test, P > 0.0001). By multivariate analysis, filtered P wave duration > 130 msec was an independent predictor of recurrence of PAF after ablation (Chi‐square = 21.5, P > 0.0001). Conclusion: The results of this study indicate that P‐SAECG may be useful for identifying patients at risk for recurrence of PAF after successful ablation of WPW syndrome.</abstract><qualityIndicators><score>6.894</score><pdfVersion>1.2</pdfVersion><pdfPageSize>583.087 x 776.126 pts</pdfPageSize><refBibsNative>false</refBibsNative><keywordCount>5</keywordCount><abstractCharCount>1716</abstractCharCount><pdfWordCount>3894</pdfWordCount><pdfCharCount>23964</pdfCharCount><pdfPageCount>6</pdfPageCount><abstractWordCount>268</abstractWordCount></qualityIndicators><title>P Wave Signal‐Averaged Electrocardiography Predicts Recurrence of Paroxysmal Atrial Fibrillation in Patients with Wolff‐Parkinson‐White Syndrome Who Underwent Successful Catheter Ablation: A Prospective Study</title><genre><json:string>review-article</json:string></genre><host><volume>13</volume><publisherId><json:string>JCE</json:string></publisherId><pages><total>6</total><last>1008</last><first>1003</first></pages><issn><json:string>1045-3873</json:string></issn><issue>10</issue><genre><json:string>Journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1540-8167</json:string></eissn><title>Journal of Cardiovascular 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with Wolff‐Parkinson‐White Syndrome Who Underwent Successful Catheter Ablation: A Prospective Study</title><respStmt xml:id="ISTEX-API" resp="Références bibliographiques récupérées via GROBID" name="ISTEX-API (INIST-CNRS)"></respStmt></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Blackwell Science Inc</publisher><pubPlace>Oxford, UK</pubPlace><availability><p>WILEY</p></availability><date>2002</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">P Wave Signal‐Averaged Electrocardiography Predicts Recurrence of Paroxysmal Atrial Fibrillation in Patients with Wolff‐Parkinson‐White Syndrome Who Underwent Successful Catheter Ablation: A Prospective Study</title><author><persName><forename type="first">TATSURO</forename><surname>HIRAKI</surname></persName><roleName type="degree">M.D., Ph.D.</roleName><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation></author><author><persName><forename type="first">HISAO</forename><surname>IKEDA</surname></persName><roleName type="degree">M.D., Ph.D.</roleName><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation></author><author><persName><forename type="first">TERUHISA</forename><surname>YOSHIDA</surname></persName><roleName type="degree">M.D., Ph.D.</roleName><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation></author><author><persName><forename type="first">TOMOHITO</forename><surname>INAGE</surname></persName><roleName type="degree">M.D.</roleName><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation></author><author><persName><forename type="first">MASATSUGU</forename><surname>OHE</surname></persName><roleName type="degree">M.D.</roleName><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation></author><author><persName><forename type="first">HITOSHI</forename><surname>OHTSUBO</surname></persName><roleName type="degree">M.D.</roleName><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation></author><author><persName><forename type="first">MANABU</forename><surname>MATSUMOTO</surname></persName><roleName type="degree">M.D.</roleName><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation></author><author><persName><forename type="first">TAKASHI</forename><surname>HAMADA</surname></persName><roleName type="degree">M.D.</roleName><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation></author><author><persName><forename type="first">ICHIRO</forename><surname>KUBARA</surname></persName><roleName type="degree">M.D., Ph.D.</roleName><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation></author><author><persName><forename type="first">TSUTOMU</forename><surname>IMAIZUMI</surname></persName><roleName type="degree">M.D., Ph.D.</roleName><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation></author></analytic><monogr><title level="j">Journal of Cardiovascular Electrophysiology</title><idno type="pISSN">1045-3873</idno><idno type="eISSN">1540-8167</idno><idno type="DOI">10.1111/(ISSN)1540-8167</idno><imprint><publisher>Blackwell Science Inc</publisher><pubPlace>Oxford, UK</pubPlace><date type="published" when="2002-10"></date><biblScope unit="volume">13</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="1003">1003</biblScope><biblScope unit="page" to="1008">1008</biblScope></imprint></monogr><idno type="istex">5A66D1B186FCDEDD4654A98DA99AD22D0A97BFA0</idno><idno type="DOI">10.1046/j.1540-8167.2002.01003.x</idno><idno type="ArticleID">JCE1003</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>2002</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>P‐SAECG Predicts Recurrence of PAF After Ablation. Introduction: Paroxysmal atrial fibrillation (PAF) frequently occurs in patients with Wolff‐Parkinson‐White (WPW) syndrome. Catheter ablation of the accessory pathway eliminates PAF in some patients, but PAF frequently recurs in other patients. The present study was designed to determine prospectively whether P wave signal‐averaged electrocardiography (P‐SAECG) predicts the recurrence of PAF after successful ablation in patients with WPW syndrome. Methods and Results: Forty‐six patients with WPW syndrome who had episodes of PAF were prospectively followed. SAECG recording was performed on day 7 after successful ablation of the accessory pathway at study entry. Abnormal P‐SAECG for the prediction of recurrence of PAF was defined as a filtered P wave duration > 130 msec. Eleven patients had an abnormal P‐SAECG (group 1), whereas 35 patients (group 2) did not. The two groups did not differ in terms of gender, age, left atrial dimension, and atrial vulnerability as determined by electrophysiologic study. During follow‐up (40 ± 19 months), the recurrence of PAF was noted in 10 (91%) of 11 patients in group 1, whereas it was observed in only 2 (6%) of 35 patients in group 2. Kaplan‐Meier analysis revealed that the recurrence of PAF was significantly more frequent in group 1 than in group 2 (log rank test, P < 0.0001). By multivariate analysis, filtered P wave duration > 130 msec was an independent predictor of recurrence of PAF after ablation (Chi‐square = 21.5, P < 0.0001). Conclusion: The results of this study indicate that P‐SAECG may be useful for identifying patients at risk for recurrence of PAF after successful ablation of WPW syndrome.</p></abstract><textClass xml:lang="en"><keywords scheme="keyword"><list><head>Keywords</head><item><term>Wolff‐Parkinson‐White syndrome</term></item><item><term>atrial fibrillation</term></item><item><term>catheter ablation</term></item><item><term>recurrence</term></item><item><term>prospective study</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="2002-10">Published</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2016-3-3">References added</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/5A66D1B186FCDEDD4654A98DA99AD22D0A97BFA0/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Wiley component found"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="yes"</istex:xmlDeclaration><istex:document><component version="2.0" type="serialArticle" xml:lang="en"><header><publicationMeta level="product"><publisherInfo><publisherName>Blackwell Science Inc</publisherName><publisherLoc>Oxford, UK</publisherLoc></publisherInfo><doi origin="wiley" registered="yes">10.1111/(ISSN)1540-8167</doi><issn type="print">1045-3873</issn><issn type="electronic">1540-8167</issn><idGroup><id type="product" value="JCE"></id><id type="publisherDivision" value="ST"></id></idGroup><titleGroup><title type="main" sort="JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY">Journal of Cardiovascular Electrophysiology</title></titleGroup></publicationMeta><publicationMeta level="part" position="10010"><doi origin="wiley">10.1111/jce.2002.13.issue-10</doi><numberingGroup><numbering type="journalVolume" number="13">13</numbering><numbering type="journalIssue" number="10">10</numbering></numberingGroup><coverDate startDate="2002-10">October 2002</coverDate></publicationMeta><publicationMeta level="unit" type="reviewArticle" position="0100300" status="forIssue"><doi origin="wiley">10.1046/j.1540-8167.2002.01003.x</doi><idGroup><id type="unit" value="JCE1003"></id></idGroup><countGroup><count type="pageTotal" number="6"></count></countGroup><titleGroup><title type="tocHeading1">Original Articles</title></titleGroup><copyright>© Futura Publishing Company, Inc. 2002</copyright><eventGroup><event type="firstOnline" date="2003-08-12"></event><event type="publishedOnlineFinalForm" date="2003-08-12"></event><event type="xmlConverted" agent="Converter:BPG_TO_WML3G version:2.3.2 mode:FullText source:Header result:Header" date="2010-03-10"></event><event type="xmlConverted" agent="Converter:WILEY_ML3G_TO_WILEY_ML3GV2 version:3.8.8" date="2014-01-29"></event><event type="xmlConverted" agent="Converter:WML3G_To_WML3G version:4.1.7 mode:FullText,remove_FC" date="2014-10-23"></event></eventGroup><numberingGroup><numbering type="pageFirst" number="1003">1003</numbering><numbering type="pageLast" number="1008">1008</numbering></numberingGroup><correspondenceTo>Address for correspondence: Tatsuro Hiraki, M.D., Department of Internal Medicine III, Kurume University School of Medicine, 67 Asahi‐machi, Kurume 830–0011, Japan. Fax: 81‐942‐33‐6509; E‐mail: <email normalForm="thiraki@med.kurume-u.ac.jp">thiraki@med.kurume‐u.ac.jp</email></correspondenceTo><linkGroup><link type="toTypesetVersion" href="file:JCE.JCE1003.pdf"></link></linkGroup></publicationMeta><contentMeta><unparsedEditorialHistory>Manuscript received 29 April 2002; Accepted for publication 20 August 2002.</unparsedEditorialHistory><titleGroup><title type="main">P Wave Signal‐Averaged Electrocardiography Predicts Recurrence of Paroxysmal Atrial Fibrillation in Patients with Wolff‐Parkinson‐White Syndrome Who Underwent Successful Catheter Ablation: A Prospective Study</title></titleGroup><creators><creator creatorRole="author" xml:id="cr1" affiliationRef="#a1"><personName><givenNames>TATSURO</givenNames><familyName>HIRAKI</familyName><degrees>M.D., Ph.D.</degrees></personName></creator><creator creatorRole="author" xml:id="cr2" affiliationRef="#a1"><personName><givenNames>HISAO</givenNames><familyName>IKEDA</familyName><degrees>M.D., Ph.D.</degrees></personName></creator><creator creatorRole="author" xml:id="cr3" affiliationRef="#a1"><personName><givenNames>TERUHISA</givenNames><familyName>YOSHIDA</familyName><degrees>M.D., Ph.D.</degrees></personName></creator><creator creatorRole="author" xml:id="cr4" affiliationRef="#a1"><personName><givenNames>TOMOHITO</givenNames><familyName>INAGE</familyName><degrees>M.D.</degrees></personName></creator><creator creatorRole="author" xml:id="cr5" affiliationRef="#a1"><personName><givenNames>MASATSUGU</givenNames><familyName>OHE</familyName><degrees>M.D.</degrees></personName></creator><creator creatorRole="author" xml:id="cr6" affiliationRef="#a1"><personName><givenNames>HITOSHI</givenNames><familyName>OHTSUBO</familyName><degrees>M.D.</degrees></personName></creator><creator creatorRole="author" xml:id="cr7" affiliationRef="#a1"><personName><givenNames>MANABU</givenNames><familyName>MATSUMOTO</familyName><degrees>M.D.</degrees></personName></creator><creator creatorRole="author" xml:id="cr8" affiliationRef="#a1"><personName><givenNames>TAKASHI</givenNames><familyName>HAMADA</familyName><degrees>M.D.</degrees></personName></creator><creator creatorRole="author" xml:id="cr9" affiliationRef="#a1"><personName><givenNames>ICHIRO</givenNames><familyName>KUBARA</familyName><degrees>M.D., Ph.D.</degrees></personName></creator><creator creatorRole="author" xml:id="cr10" affiliationRef="#a1"><personName><givenNames>TSUTOMU</givenNames><familyName>IMAIZUMI</familyName><degrees>M.D., Ph.D.</degrees></personName></creator></creators><affiliationGroup><affiliation xml:id="a1" countryCode="JP"><unparsedAffiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</unparsedAffiliation></affiliation></affiliationGroup><keywordGroup xml:lang="en"><keyword xml:id="k1">Wolff‐Parkinson‐White syndrome</keyword><keyword xml:id="k2">atrial fibrillation</keyword><keyword xml:id="k3">catheter ablation</keyword><keyword xml:id="k4">recurrence</keyword><keyword xml:id="k5">prospective study</keyword></keywordGroup><abstractGroup><abstract type="main" xml:lang="en"><p> <b>P‐SAECG Predicts Recurrence of PAF After Ablation.</b><i>Introduction</i>: Paroxysmal atrial fibrillation (PAF) frequently occurs in patients with Wolff‐Parkinson‐White (WPW) syndrome. Catheter ablation of the accessory pathway eliminates PAF in some patients, but PAF frequently recurs in other patients. The present study was designed to determine prospectively whether P wave signal‐averaged electrocardiography (P‐SAECG) predicts the recurrence of PAF after successful ablation in patients with WPW syndrome.</p><p> <i>Methods and Results</i>: Forty‐six patients with WPW syndrome who had episodes of PAF were prospectively followed. SAECG recording was performed on day 7 after successful ablation of the accessory pathway at study entry. Abnormal P‐SAECG for the prediction of recurrence of PAF was defined as a filtered P wave duration > 130 msec. Eleven patients had an abnormal P‐SAECG (group 1), whereas 35 patients (group 2) did not. The two groups did not differ in terms of gender, age, left atrial dimension, and atrial vulnerability as determined by electrophysiologic study. During follow‐up (<span type="mathematics">40 ± 19 months</span>), the recurrence of PAF was noted in 10 (91%) of 11 patients in group 1, whereas it was observed in only 2 (6%) of 35 patients in group 2. Kaplan‐Meier analysis revealed that the recurrence of PAF was significantly more frequent in group 1 than in group 2 (log rank test, <span type="mathematics">P < 0.0001</span>). By multivariate analysis, filtered P wave duration > 130 msec was an independent predictor of recurrence of PAF after ablation (<span type="mathematics">Chi‐square = 21.5, P < 0.0001</span>).</p><p> <i>Conclusion</i>: The results of this study indicate that P‐SAECG may be useful for identifying patients at risk for recurrence of PAF after successful ablation of WPW syndrome.</p><!-- (J Cardiovasc Electrophysiol, Vol. 13, pp. 1003–1008, October 2002)
</abstractGroup></contentMeta></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>P Wave Signal‐Averaged Electrocardiography Predicts Recurrence of Paroxysmal Atrial Fibrillation in Patients with Wolff‐Parkinson‐White Syndrome Who Underwent Successful Catheter Ablation: A Prospective Study</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>P Wave Signal‐Averaged Electrocardiography Predicts Recurrence of Paroxysmal Atrial Fibrillation in Patients with Wolff‐Parkinson‐White Syndrome Who Underwent Successful Catheter Ablation: A Prospective Study</title></titleInfo><name type="personal"><namePart type="given">TATSURO</namePart><namePart type="family">HIRAKI</namePart><namePart type="termsOfAddress">M.D., Ph.D.</namePart><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HISAO</namePart><namePart type="family">IKEDA</namePart><namePart type="termsOfAddress">M.D., Ph.D.</namePart><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">TERUHISA</namePart><namePart type="family">YOSHIDA</namePart><namePart type="termsOfAddress">M.D., Ph.D.</namePart><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">TOMOHITO</namePart><namePart type="family">INAGE</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MASATSUGU</namePart><namePart type="family">OHE</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">HITOSHI</namePart><namePart type="family">OHTSUBO</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">MANABU</namePart><namePart type="family">MATSUMOTO</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">TAKASHI</namePart><namePart type="family">HAMADA</namePart><namePart type="termsOfAddress">M.D.</namePart><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">ICHIRO</namePart><namePart type="family">KUBARA</namePart><namePart type="termsOfAddress">M.D., Ph.D.</namePart><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">TSUTOMU</namePart><namePart type="family">IMAIZUMI</namePart><namePart type="termsOfAddress">M.D., Ph.D.</namePart><affiliation>Department of Internal Medicine III and the Cardiovascular Research Institute, Kurume University School of Medicine, Kurume, Japan</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="review-article" displayLabel="reviewArticle"></genre><originInfo><publisher>Blackwell Science Inc</publisher><place><placeTerm type="text">Oxford, UK</placeTerm></place><dateIssued encoding="w3cdtf">2002-10</dateIssued><edition>Manuscript received 29 April 2002; Accepted for publication 20 August 2002.</edition><copyrightDate encoding="w3cdtf">2002</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">P‐SAECG Predicts Recurrence of PAF After Ablation. Introduction: Paroxysmal atrial fibrillation (PAF) frequently occurs in patients with Wolff‐Parkinson‐White (WPW) syndrome. Catheter ablation of the accessory pathway eliminates PAF in some patients, but PAF frequently recurs in other patients. The present study was designed to determine prospectively whether P wave signal‐averaged electrocardiography (P‐SAECG) predicts the recurrence of PAF after successful ablation in patients with WPW syndrome. Methods and Results: Forty‐six patients with WPW syndrome who had episodes of PAF were prospectively followed. SAECG recording was performed on day 7 after successful ablation of the accessory pathway at study entry. Abnormal P‐SAECG for the prediction of recurrence of PAF was defined as a filtered P wave duration > 130 msec. Eleven patients had an abnormal P‐SAECG (group 1), whereas 35 patients (group 2) did not. The two groups did not differ in terms of gender, age, left atrial dimension, and atrial vulnerability as determined by electrophysiologic study. During follow‐up (40 ± 19 months), the recurrence of PAF was noted in 10 (91%) of 11 patients in group 1, whereas it was observed in only 2 (6%) of 35 patients in group 2. Kaplan‐Meier analysis revealed that the recurrence of PAF was significantly more frequent in group 1 than in group 2 (log rank test, P < 0.0001). By multivariate analysis, filtered P wave duration > 130 msec was an independent predictor of recurrence of PAF after ablation (Chi‐square = 21.5, P < 0.0001). Conclusion: The results of this study indicate that P‐SAECG may be useful for identifying patients at risk for recurrence of PAF after successful ablation of WPW syndrome.</abstract><subject lang="en"><genre>Keywords</genre><topic>Wolff‐Parkinson‐White syndrome</topic><topic>atrial fibrillation</topic><topic>catheter ablation</topic><topic>recurrence</topic><topic>prospective study</topic></subject><relatedItem type="host"><titleInfo><title>Journal of Cardiovascular Electrophysiology</title></titleInfo><genre type="Journal">journal</genre><identifier type="ISSN">1045-3873</identifier><identifier type="eISSN">1540-8167</identifier><identifier type="DOI">10.1111/(ISSN)1540-8167</identifier><identifier type="PublisherID">JCE</identifier><part><date>2002</date><detail type="volume"><caption>vol.</caption><number>13</number></detail><detail type="issue"><caption>no.</caption><number>10</number></detail><extent unit="pages"><start>1003</start><end>1008</end><total>6</total></extent></part></relatedItem><identifier type="istex">5A66D1B186FCDEDD4654A98DA99AD22D0A97BFA0</identifier><identifier type="DOI">10.1046/j.1540-8167.2002.01003.x</identifier><identifier type="ArticleID">JCE1003</identifier><accessCondition type="use and reproduction" contentType="copyright">© Futura Publishing Company, Inc. 2002</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Blackwell Science Inc</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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